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From : AstraZeneca

PRODUCT DISCONTINUATION NOTICE

As a follow -up to a communication sent to you this summer, AstraZeneca would like to advise you that RHINOCORT® (budesonide) Nasal Inhaler (NDC #0186-1075-09) will no longer be shipped by AstraZeneca as of November 15, 2002.  Please not that you may continue dispensing existing stock of RHINOCORT Nasal Inhaler until your supplies have been exhausted.

This product does NOT affect RHINOCORT AQUA® (budesonide) Nasal Spray (8.4 mL/ 120-metered dose spray bottles), NDC #0186-0170-08.  Physicians may wish to switch their appropriate allergic rhinitis patients to RHINOCORT AQUA as another treatment option.

Enclosed for you use during this phase out period is a card that may be displayed on your pharmacy shelf, where RHINOCORT Nasal Inhaler is stored.

RHINOCORT AQUA  is indicated for the management of nasal symptoms of seasonal and perennial allergic rhinitis in adults and children 6 years and older.  The recommended starting dosage is 1 spray per nostril once daily (64-mcg total daily dose), with individualized dosing up to 256 mcg for adults and 128 mcg for children aged 6 to 12 years. 

In clinical trials, commonly reported adverse events with RHINOCORT AQUA versus placebo were epistaxis (8% vs 5%), pharyngitis (4% vs 3%), bronchospasm (2% vs 1%), coughing (2% vs 1%), and nasal irritation (2% vs <1%).  The overall incidence of adverse events with RHINOCORT AQUA was similar to that observed with vehicle placebo.

RHINOCORT Nasal Inhaler is indicated for the management of symptoms of seasonal or perennial allergic rhinitis in adults and children 6 years and older and nonallergenic perennial rhinitis in adults.  In clinical trials, commonly reported adverse events with RHINOCORT Nasal Inhaler included nasal irritation, pharyngitis, increased cough, and epistaxis (all occurring at an incidence of 3% to 9%).

Please see enclosed full Prescribing information for RHINOCORT AQUA and RHINOCORT Nasal Inhaler.

If you would like more information about RHINOCORT AQUA, please visit our web site, www.rhinocortaqua.com.

AstraZeneca recognizes the important role that pharmacists have in providing information to their patients regarding prescribed medications.  We appreciate your commitment to keeping your patients informed  about changes in the products that are available to them.

If you have any questions, please contact your servicing wholesaler, or the AstraZeneca Customer Service Department at 1-800-842-9920.

Sincerely,

James F. Liebman                                                                                                                                                                                                                          Sales Director, Managed Care                                                                                                                                                                                                     Trade Sales

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FROM: NATURE MADE                                                        06-26-03 LDL cholesterol plummets as much as 24% without a prescription Have you noticed that more often these days, Americans with higher cholesterol levels are looking for a natural alternative to prescription medications? They want results, but they're worried about possible side effects and drug interactions. Lower cholesterol without filling a prescription Now, you can recommend a proven solution: Cholest-Off™ from Nature  Made.® This all-natural supplement is a drug-free blend of plant sterols and stanols, which is clinically proven to reduce cholesterol levels as much as 24% in 30 days* in conjunction with a low-fat diet and exercise.1 All-natural cholesterol fighter as safe as it is effective Inn addition to working quickly, Cholest-Off is safe. Unlike prescriptions which can cause liver dysfunction, muscle pain or weakness, and constipation, 2-4 Cholest-Off has no significant side effects or drug interactions. After all, its ingredients are extracted from plants, making it a safe alternative. When it's your recommendation, trust Nature Made Nature made has always guaranteed the quality of every vitamin, mineral, and supplement. Recently, these high standards enabled it to become the first to earn the USP Verification for Dietary Supplements. So when you tell customers about Cholest-Off from Nature Made, you can be sure they will be choosing a high-quality product worthy of your recommendation. If you want more information about the natural cholesterol fighter, call us at 1-800-276-2878 or visit www.NatureMade.com. 1. Jones P, et al. Am J Clin Nutr.  1999;69:1144-1150 2. Lipitor® (atorcastatin calcium) tablets full prescribing information. Dublin, Ireland: Pfizer Ireland Pharmaceuticals; 2002. 3. Zocor® (simvastatin) full prescribing information. Whitehouse Station, NJ: Merck & Co., Inc.; 2002. 4. Pravachol® (pravastatin) full prescribing information. Princeton, NJ: Bristol-Myers Squibb Company; 2002.  *(Study was conducted on Reducol, the proprietary blend of plant sterols and stanols in Cholest-Off. The average reduction range in LDL cholesterol in 6 clinical studies on Reducol is 4.2%-24%. Individual results may vary.

May 2nd, 2006

Official complaint of Unfair Business Practices and Severe Client Confidentiality violations by Meerdink & Associates and Russell Meerdink himself filed to the Greenville Market Condo Association by RxLink Pharmacy.  These unfair business practices are now being reported to State and Federal agencies for proper review. For more information, please contact the Town of Greenville, Wisconsin.

07/12/05 From: TAP Pharmaceutical ---- Prevacid                                                  Here is some information that can help your patients with GERD. PREVACID is FDA approved for GERD in adolescents 12-17 years old, in addition to children 12 months-11 years old. PREVACID provides the most FDA-approved oral administration options of any PPI including strawberry-flavored PREVACID SOLUTAB (lansoprazole), the only PPI available an orally disintegrating tablet. PREVACID SOLUTAB is bioequivalent to PREVACID capsules, and it's easy to take. SoluTab quickly disintegrates in the mouth-with or without water-usually in less than 60 seconds. And PREVACID SoluTab can be administered in three different ways: -Orally disintegrating tablet -Nasogastric tube (> 8 French) -Oral syringe The safety and effectiveness of PREVACID have been established in patients 1 o 17 years of age for the short-term treatment of symptomatic and erosive GERD. Individual results may vary. Use of PREVACID in this age group is supported by evidence from adequate and well-controlled studies in adults along with additional clinical and PK/PD studies performed in pediatric patients. The pediatric studies were uncontrolled open-label studies performed in 66 patients aged 1 to 11 years old and 87 patients aged 12 to 17 years old. The safety and effectiveness of PREVACID have not been established in patents <1 year of age. The most frequently reported adverse events in patients aged 1 to 11 years old were constipation (5%) and headache (7%), abdominal pain (5%), nausea (3%), and dizziness (#%). In adults, the most frequently reported adverse events were diarrhea (3.8%), abdominal pain (2.1%), and nausea (1.3%). Symptomatic response to therapy does not preclude the presence of gastric malignancy. PREVACID is contraindicated in patients with known hypersensitivity to any component of the formulation. For additional information about Prevacid SoluTab, including details on administration options, please see the accompanying complete prescribing information for PREVACID, contact your TAP representative, visit www.prevacid.com, or call TAP Medical Information at 1-800-622-2011. Sincerely, Lawrence Staubach, MD Director, Medical Affairs P.S. PREVACID delivers comforting relief to more kids, in more ways. For ordering information, contact your wholesaler today!